The village lies 5.5 kilometres southeast from Spili, tucked into the hillside at the base of Mount Kedros on the south facing slopes of a spectacular valley, 1 kilometre up from the road that leads to Ag. Galini. At an altitude of 589 metres, Kissos has splendid mountain views; it is a traditional country Cretan village, laced with narrow roads and alleyways, it has little or no modern development. In the last census in 1991 the population had dropped to 126, today it remains a small friendly community. There are three churches, Sotiras Christos, Panagia and the church of Agios Ioannis that has interesting Frescos. On the outskirts of the village is the old Byzantine Monastery of Ag. Pnevma (Holy Spirit) whose church is still preserved.
All local amenities can be found in the busy mountain town of Spili, including a health centre, bank and several supermarkets, also close by is the village of Akoumia that has plenty of tavernas and cafes. There is an excellent choice of beaches in the area, ranging from the popular beach at the small resort of Ag. Galini, to some of the beautiful and undeveloped beaches around Triopetra and Ligres, these are reached by a short drive over the mountain. For those who love walking and have an interest in the local flora, Kissos is situated just off the European walkway. The town of Rethymno is 33km to the north and driving time to both Hania and Heraklion airports is approximately one and a half hours.